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The balance between ROS production and antioxidant capacity also affects the developmental competence of oocytes

The pathogenesis and the pathophysiology of sepsis is very complicated and multifaceted: numerous biological mechanisms, such as infection, inflammation, oxidative stress, immune system dysregulation, blood coagulation, endothelium dysfunction, tissue damage, elevated cellular death and/or apoptosis are involved during sepsis at tissue, cellular and molecular levels causing a damaging systemic reaction [379]

Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells

10.1016/j.brainres.2019.05.007 21 IlariS.GiancottiL

This interaction reinforces the gut barrier and reduces pro-inflammatory cytokine secretion (148), and enhances immune responses (149)